Subdirección de Investigación Biomédica
Departamento de Investigación Básica
Investigador en Ciencias Médicas "D"
allbioexp@yahoo.com
armando.luna@salud.gob.mx
  1. Doctorado: Biología Experimental, Universidad Autónoma Metropolitana, Unidad Iztapalapa.
  2. Maestría: Biología Experimental, Universidad Autónoma Metropolitana, Unidad Iztapalapa
  3. Licenciatura: Biología Experimental, Universidad Autónoma Metropolitana.
  1. Mecanismos moleculares del envejecimiento
  2. Estrés oxidante y envejecimiento
  3. Envejecimiento y cáncer
  1. Mecanismo de la respuesta hormética antioxidante en un modelo de mioblastos de rata de la línea L6. Investigadores: Dra. Mina Konigsberg Fainstein, Dr. Luis Enrique Gómez Quiroz, Dra. Norma Edith López Diazguerrero, M en BE Pedro Posadas Rodríguez. Periodo: 2014-2018.
  2. Participación del GDF11 como factor de regeneración muscular en ratas con obesidad sarcopénica asociada al envejecimiento. Investigadores: Dra. Mina Konigsberg Fainstein, Dr, Luis Enrique Gómez Quiroz, Dra. Norma Edith López Diazguerrero, Dr. Oscar Rosas Carrasco; M en C Beatriz Mena Montes, M en BE Roberto Lazzarini Lechuga, M en BE Gibrán Pedraza Vázquez, M en CG David Hernández Álvarez. Periodo: 2016-2019.
  1. Barajas-Gómez BA, Rosas-Carrasco O, Morales-Rosales SL, Pedraza Vázquez G, González-Puertos VY, Juárez-Cedillo T, García-Álvarez JA, López-Diazguerrero NE, Damián-Matsumura P, Königsberg M, Luna-López A. Relationship of inflammatory profile of elderly patients serum and senescence-associated secretory phenotype with human breast cancer cells proliferation: Role of IL6/IL8 ratio. Cytokine. 2017 Mar; 91:13-29.
  2. Maya-López M, Colín-González AL, Aguilera G, de Lima ME, Colpo-Ceolin A, Rangel-López E, Villeda-Hernández J, Rembao-Bojórquez D, Túnez I, Luna-López A, Lazzarini-Lechuga R, González-Puertos VY, Posadas-Rodríguez P, Silva-Palacios A, Königsberg M, Santamaría A. Neuroprotective effect of WIN55,212-2 against 3-nitropropionic acid-induced toxicity in the rat brain: involvement of CB1 and NMDA receptors. Am J Transl Res. 2017 Feb 15; 9(2):261-274.
  3. Silva-Palacios A, Colín-González AL, López-Cervantes SP, Zazueta C, Luna-López A, Santamaría A, Königsberg M. Tert-buthylhydroquinone pre-conditioning exerts dual effects in old female rats exposed to 3-nitropropionic acid. Redox Biol. 2017 Aug; 12:610-624.
  4. Silva-Palacios A, Ostolga-Chavarría M, Buelna-Chontal M, Garibay C, Hernández-Reséndiz S, Roldán FJ, Flores PL, Luna-López A, Königsberg M, Zazueta C. 3-NP-induced Huntington's-like disease impairs Nrf2 activation without loss of cardiac function in aged rats. Exp Gerontol. 2017 Oct 1;96:89-98.
  5. Maciel-Barón LA, Morales-Rosales SL, Aquino-Cruz AA, Triana-Martínez F, Galván-Arzate S, Luna-López A, González-Puertos VY, López-Díazguerrero NE, Torres C, Königsberg M. Senescence associated secretory phenotype profile from primary lung mice fibroblasts depends on the senescence induction stimuli. Age (Dordr). 2016 Feb; 38(1):26.
  6. Domínguez-Pérez M, Nuño-Lámbarri N, Clavijo-Cornejo D, Luna-López A, Souza V, Bucio L, Miranda RU, Muñoz L, Gomez-Quiroz LE, Uribe-Carvajal S, Gutiérrez-Ruiz MC. Hepatocyte Growth Factor Reduces Free Cholesterol-Mediated Lipotoxicity in Primary Hepatocytes by Countering Oxidative Stress. Oxid Med Cell Longev. 2016; 2016:7960386.
  7. Trejo-Vargas A, Hernández-Mercado E, Ordóñez-Razo RM, [...], Königsberg M, Luna-López A.Bik subcellular localization in response to oxidative stress induced by chemotherapy, in Two different breast cancer cell lines and a Non-tumorigenic epithelial cell line. Journal of Applied Toxicology 2015. Nov;35(11):1262-70.
  8. Gavia-García G, González-Martínez H, Miliar-García Á, Bonilla-González E, Rosas-Trejo M de L, Königsberg M, Nájera-Medina O, Luna-López A, González-Torres MC. Oxidative damage and antioxidant defense in thymus of malnourished lactating rats. Nutrition. 2015 Nov-Dec; 31(11-12):1408-15
  9. Alarcon-Aguilar A, Luna-López A, et al. Comparing the effects of two neurotoxins in cortical astrocytes obtained from rats of different ages: involvement of oxidative damage. J Appl Toxicol 34, 127-138 (2014).
  10. Colin-González AL, Luna-López A, et al. Early Modulation of the Transcription Factor Nrf2 in Rodent Striatal Slices by Quinolinic Acid, a Toxic Metabolite of the Kynurenine Pathway.Neuroscience 260, 130-139 (2014).
  11. Alarcón-Aguilar A, Luna-López A, Ventura-Gallegos JL, Lazzarini R, Galván-Arzate S, González-Puertos VY, Morán J, Santamaría A, Königsberg M. Primary cultured astrocytes from old rats are capable to activate the Nrf2 response against MPP+ toxicity after tBHQ pretreatment.Neurobiol Aging.35(8)1901-12,2014
  12. Luna-López A, González-Puertos VY, López-Diazguerrero NE, Königsberg M. New considerations on hormetic response against oxidative stress. J Cell Commun Signal.8(4)323-331.2014
  13. Jiménez-Salazar JE, Posadas-Rodríguez P, Lazzarini-Lechuga RC, Luna-López A, Zentella-Dehesa A, Gómez-Quiroz LE, Königsberg M, Domínguez-Gómez G, Damián-Matsumura P. Membrane-Initiated Estradiol Signaling of Epithelial-Mesenchymal Transition-Associated Mechanisms Through Regulation of Tight Junctions in Human Breast Cancer Cells. Horm Cancer. 2014 5(3) 161-73
  14. Luna-López A, et al. A noncanonical NF-kappaB pathway through the p50 subunit regulates Bcl-2 overexpression during an oxidative-conditioning hormesis response. Free Radical Biology and Medicine 63, 41-50 (2013).
  15. López-Diaz guerrero NE, González Puertos VY, Hernández-Bautista RJ, Alarcón A, Luna-López A, Königsberg Fainstein M. Hormesis: What doesnt kill you makes you stronger. Gaceta Medica de México 149 (4) 438-447 (2013).
  16. Conde-Perezprina JC, Luna-López A, et al. DNA MMR systems, microsatellite instability and antioxidant activity variations in two species of wild bats: Myotis velifer and Desmodus rotundus, as possible factors associated with longevity. Age (Dordr) 34, 1473-1492 (2012).
  17. López-Diazguerrero NE, Luna-López A, et al. Telomerase activity in response to mild oxidative stress. Cell Biol Int 36, 409-413 (2012).
  18. Luna-López A, Tasset I, Pérez-De La Cruz V, Elinos-Calderón D, Carrillo-Andrade P, Konigsberg M, Pedraza-Chaverrí J, Maldonado PD, Ali SF, Túnez I, Santamaría A. Protective Effect of Tert-Butylhidroquinone on the Quinolinic Acid-Induced Toxicity in Rat Striatal Slices: Role of the NRF2-ARE Pathway Neurosignals 2010 18(1) : 24-31
  19. Luna-López A, Triana-Martínez F, López-Diazguerrero NE, Ventura-Gallegos JL, Gutiérrez-Ruiz MC, Damián-Matsumura P, Zentella A, Gómez-Quiroz LE, Königsberg M. Bcl-2 sustains hormetic response by inducing Nrf-2 nuclear translocation in L929 mouse fibroblasts. Free radical biology and medicine 49(7) 1192-204 (2010)
  1. Universidad Autónoma Metropolitana, Unidad Iztapalapa Curso: Licenciatura: Química General; Seminario de Investigación I, II, II; Trabajo Experimental I, II, III; Biología Experimental I, II, III.
  2. Universidad Autónoma Metropolitana, Unidad Iztapalapa Curso: Posgrado: Biología Experimental I, II, III.
  1. Medical College of Georgia, 2009.